ER Progression and Resistance: Causes, Consequences, and Hope

ER Progression and Resistance: Causes, Consequences, and Hope

Endocrine therapy is an effective way to treat hormone-sensitive breast cancers, but de novo and acquired resistance to this treatment remains a major challenge. In this episode, the Our MBC Life team hears from two dynamic MSK oncologists Dr. Pedram Razavi and Dr. Komal Jhaveri on treatment strategies and the latest research around the problem of endocrine resistance.

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Dr. Stephanie Graff: Understanding Progression
Doing End-Of-Life Right
Dr. Priya Kumthekar: Glimpses of Hope for Leptomeningeal Metastases

Dr. Priya Kumthekar: Glimpses of Hope for Leptomeningeal Metastases

Co-hosts Victoria Goldberg and Dr. Paula Jayne sit down with neuro-oncologist Dr. Priya Kumthekar to talk about leptomeningeal metastases: what they are, how are they treated, and what research is upcoming, including a discussion on ANGled, the new Phase 3 trial for MBC patients newly diagnosed with leptomeningeal metastases.

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Dr. Timothy Pluard: the Future of MBC Care is Already Here

Dr. Timothy Pluard: the Future of MBC Care is Already Here

The future of personalized care for those living with MBC is already here, and it is happening in Kansas City, Missouri. Dr. Timothy Pluard, Medical Director of the Kansas City’s Saint Luke’s Koontz Center for Advanced Breast Cancer is with us today and we’ll ask him how he and his team create an individualized, completely comprehensive plan for each woman.

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Report Back from SABCS 2021: What’s the Latest in MBC Research?

Report Back from SABCS 2021: What’s the Latest in MBC Research?

Learn about the most recent information released at the annual San Antonio Breast Cancer Symposium regarding metastatic breast cancer research with Dr. Peter Schmid, Professor of Cancer Medicine at Barts Cancer Institute in London, England. Dr. Schmid will provide a comprehensive update and answer your questions about these new developments.

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MBC101 - what happens when MBC spreads to the brain?

MBC101 - what happens when MBC spreads to the brain?

On 10/12/21  Lianne Kraemer, an MBC patient advocate living with brain mets , and SHARE hosted two brilliant young clinicians from Moffitt in a discussion on management of breast cancer brain metastases. Today we are bringing you this webinar with our additional commentary. We will let you in on a little secret. This episode is a glimpse into how we envision the next season’s Road to a Cure. It will include more content with an educational angle for the newly diagnosed or those who are ready to take a deeper dive with us into the basics. We call it MBC101.

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Road to a Cure - drug resistance

Road to a Cure - drug resistance

It is fitting that our 7th and last stop before the SABCS is back to NYC. Co-hosts Lisa Laudico and Ellen Landsberger talk with Dr Sarat Chandarlapaty, a leading Physician Scientist at MSKCC. As both a physician treating patients and a scientist in the lab, Dr. Chandarlapaty gives us an understanding of translational medicine, transferring what he learns from his patients back into the lab to answer questions that advance the treatment of metastatic breast cancer.

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Road to a Cure - ABC with Dr. Fatima Cardoso

Road to a Cure - ABC with Dr. Fatima Cardoso

This is the sixth stop in our series Road to a Cure. From the start our goal for this series was not only to educate and give hope to every listener but also to ensure that each of these special interviews feels like an intimate conversation with our smartest friend who also happens to be an oncologist researcher. This episode will not disappoint., Co-hosts Victoria Goldberg and Lisa Laudico, sit down with the Director of the Breast Unit of the Champalimaud Clinical Center in Lisbon, Portugal, Dr. Fatima Cardoso.

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Road to a Cure - ADC & SARM

Road to a Cure - ADC & SARM

How famous is Dr Hope Rugo? She belongs to a tiny elite group of oncologists who have their own Wikipedia page. Dr. Dennis Slamon is quite possibly the only other member. Enough said. No surprise that we can’t wait to hear what she has to say about a new class of drugs, known as ADCs and specifically, the first ADC for mTNBC that already has a nickname – Sassy (sacituzumab govitecan). Do you know what a SARM is? It is a special class of drugs for those who are Androgen Receptor (AR) positive. Listen and find out.

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Body Image & Diet Culture

Body Image & Diet Culture

Our episode this week will focus on body image and diet culture, both within society and the breast cancer community, and how treatment can affect our feelings about our bodies. Co-host Natalia Green moderates a panel of women currently living with MBC who discuss and share their experiences.

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Road to a Cure - use of immunotherapy

Road to a Cure - use of immunotherapy

This week we are visiting Dr Stephanie Goff at the NIH in Bethesda, Maryland. Dr Goff is a surgical oncologist and a senior member of a research team led by Dr. Steven A. Rosenberg, a man widely regarded as the father of immunotherapy. A friend, who knows a thing or two about this place. is joining us on this trip. Her name is Judy Perkins, and she is the first MBC patient who has been cured by a revolutionary immunotherapy treatment, known as adoptive cell therapy, that was administered by Dr Goff and her colleagues at the NCI.

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Road to a Cure - Dr. Heather Parsons & Dr. Nancy Lin

Road to a Cure - Dr. Heather Parsons & Dr. Nancy Lin

The Road to a Cure series heads to Boston to have Senior Producer and Co-host, Victoria Goldberg and co-host Dr. Paula Jayne speak with Dr. Nancy Lin and Dr. Heather Parsons about the possibilities and the current barriers to considering a cure for HER2+ MBC. Dr. Parsons and Dr. Lin are medical oncologists and professors at Harvard Medical School. Dr. Lin is also the Director of the Metastatic Breast Cancer Program and the Associate Chief of the Division of Breast Oncology at Dana Farber Cancer Institute. While an amazing gift, long-term survival among some HER2+ patients can also sometimes bring special challenges. Given the higher prevalence of brain metastases among HER2+ patients, Drs. Lin and Parsons also discuss current research on brain mets, along with areas of promising overall MBC research for each subtype.

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Road to a Cure - Dr. Sara Hurvitz

Road to a Cure - Dr. Sara Hurvitz

The Road to a Cure series gets on the redeye to LA to have Senior Producer and Co-host, Victoria Goldberg and co-host Kate Pfitzer speak with Dr. Sara Hurvitz. She talks about her perspective on where we are as we work for a cure, the HER2+ studies she is excited about, and other research that is intriguing as it relates to all subtypes

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Road to a Cure - Dr. Larry Norton

Road to a Cure - Dr. Larry Norton

Our special series, Road to a Cure, makes its first stop at Memorial Sloan Kettering Cancer Center in New York, with an interview with Dr. Larry Norton. He is Senior Vice President in the Office of the President, and Deputy Director for Clinical and Translational Science in the Memorial Sloan Kettering Cancer Center. Dr. Norton’s also the Medical Director of the Evelyn H. Lauder Breast Center at MSK and a founder of the Breast Cancer Research Foundation. Senior Producer & Host Lisa Laudico and co-host Dr. Ellen Landsberger speak with Dr. Norton on what he sees happening with Metastatic Breast Cancer research today. They ask him about what lines of research are most exciting to him and also all about how he cares for his own mental health

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MBC Around the World

MBC Around the World

Grab those negative covid tests and passports because we travel around the world in this episode!  Oh yeah, get your proof of vaccination and N95s too since this thing ain’t over yet sadly.  We wanted to learn how others living with and advocating for MBC deal with it all in other places. So we travel virtually to Canada, Japan, Kuwait, Egypt, Australia, Portugal, Kenya, Nigeria, and the UK.  Co-hosts Natalia Green, Sheila McGlown, Lisa Laudico, and Anne Woodward find out what it’s like to get a second opinion in Europe & Canada, or why MBC is called Advanced Breast Cancer in some places, or how getting drugs in some countries is like applying for a car loan, or the debilitating stigma of cancer and so much more. 

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Relationships and Intimacy
Report Back from ASCO: What’s the Latest in Metastatic Breast Cancer

Report Back from ASCO: What’s the Latest in Metastatic Breast Cancer

Are you living with ER+/HER2- or TNBC MBC and tired of hearing about new HER2 therapies and wondering when it will be your turn? Just after the meeting SHARE welcomed Dr. Timothy Pluard from University of Missouri-KC School of Medicine to a webinar highlighting promising data from trials and labs across the globe presented at the this year’s meeting,

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Facing Mortality

Facing Mortality

Welcome to a special episode of our podcast. In April of 2021 a prominent clinical psychologist Dr Anne Kane joined SHARE’s Program Project Manager Deb Hackenberry in a discussion about the implications of facing mortality while also living as Dr Kane puts it as fully, richly, and deeply as possible. This episode is an audio version of the webinar about a very real, yet seldomly discussed issue.

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        The Magic of Palliative Care:       Our Stories