ER Progression and Resistance: Causes, Consequences, and Hope

ER Progression and Resistance: Causes, Consequences, and Hope

Endocrine therapy is an effective way to treat hormone-sensitive breast cancers, but de novo and acquired resistance to this treatment remains a major challenge. In this episode, the Our MBC Life team hears from two dynamic MSK oncologists Dr. Pedram Razavi and Dr. Komal Jhaveri on treatment strategies and the latest research around the problem of endocrine resistance.

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Road to a Cure - drug resistance

Road to a Cure - drug resistance

It is fitting that our 7th and last stop before the SABCS is back to NYC. Co-hosts Lisa Laudico and Ellen Landsberger talk with Dr Sarat Chandarlapaty, a leading Physician Scientist at MSKCC. As both a physician treating patients and a scientist in the lab, Dr. Chandarlapaty gives us an understanding of translational medicine, transferring what he learns from his patients back into the lab to answer questions that advance the treatment of metastatic breast cancer.

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Road to a Cure - ADC & SARM

Road to a Cure - ADC & SARM

How famous is Dr Hope Rugo? She belongs to a tiny elite group of oncologists who have their own Wikipedia page. Dr. Dennis Slamon is quite possibly the only other member. Enough said. No surprise that we can’t wait to hear what she has to say about a new class of drugs, known as ADCs and specifically, the first ADC for mTNBC that already has a nickname – Sassy (sacituzumab govitecan). Do you know what a SARM is? It is a special class of drugs for those who are Androgen Receptor (AR) positive. Listen and find out.

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Road to a Cure - Dr. Larry Norton

Road to a Cure - Dr. Larry Norton

Our special series, Road to a Cure, makes its first stop at Memorial Sloan Kettering Cancer Center in New York, with an interview with Dr. Larry Norton. He is Senior Vice President in the Office of the President, and Deputy Director for Clinical and Translational Science in the Memorial Sloan Kettering Cancer Center. Dr. Norton’s also the Medical Director of the Evelyn H. Lauder Breast Center at MSK and a founder of the Breast Cancer Research Foundation. Senior Producer & Host Lisa Laudico and co-host Dr. Ellen Landsberger speak with Dr. Norton on what he sees happening with Metastatic Breast Cancer research today. They ask him about what lines of research are most exciting to him and also all about how he cares for his own mental health

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